3'-Modified oligonucleotides


All modified DNA oligonucleotides are HPLC purified at no additional charge.
All modifications can also be introduced in RNA.

3'-Amino
3'-Cholesteryl (3'-Chol)
3'-Hexyl (3'-Hex)
3'-Phosphate (3'-Phos)
3'-Thiol


3'-Amino

  • Useful for synthesis of oligonucleotides with multiple reporter groups and markers when modifications are introduced at the 5'- and 3'-end
  • No extension by DNA-polymerases during PCR

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product scale amount cat. no. price/coupling
3'-Amino 0.05 µmol 5 nmol 5-0220-012 38.00 EUR
0.20 µmol 25 nmol 5-0220-013 48.00 EUR
1.00 µmol 100 nmol 5-0220-014 68.00 EUR

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top 3'-Cholesteryl (3'-Chol)

  • Used in antisense technology
  • The highly lipophilic compound mediates the penetration of oligonucleotides through the cell membrane

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product scale amount cat. no. price/coupling
3'-Chol 0.05 µmol 5 nmol 5-0220-112 99.00 EUR
0.20 µmol 25 nmol 5-0220-113 115.00 EUR
1.00 µmol 100 nmol 5-0220-114 165.00 EUR

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Reference


top 3'-Hexyl (3'-Hex)


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product scale amount cat. no. price/coupling
3'-Hex 0.05 µmol 5 nmol 5-0220-232 38.00 EUR
0.20 µmol 25 nmol 5-0220-233 48.00 EUR
1.00 µmol 100 nmol 5-0220-234 68.00 EUR

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top 3'-Phosphate (3'-Phos)

  • Blocks the extension of the 3'-end by polymerases (see also Real-time PCR )
  • 3'-phosphorylated oligonucleotides cannot be ligated by ligases

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product scale amount cat. no. price/coupling
3'-Phos 0.05 µmol 5 nmol 5-0220-212 38.00 EUR
0.20 µmol 25 nmol 5-0220-213 48.00 EUR
1.00 µmol 100 nmol 5-0220-214 68.00 EUR

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Reference


top 3'-Thiol


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product scale amount cat. no. price/coupling
3'-Thiol 0.05 µmol 5 nmol 5-0220-312 38.00 EUR
0.20 µmol 25 nmol 5-0220-313 48.00 EUR
1.00 µmol 100 nmol 5-0220-314 79.00 EUR

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