Oligonucleotides with internal modifications


Thymidine modifications

4-Thio-2'-deoxythymidine (4-Thio-dT)
5-C3-Carboxy-2'-deoxythymidine (5-C3-Carboxy-dT)
5-C6-Amino-2'-deoxythymidine (5-C6-Amino-dT)
Inverse-2'-deoxythymidine (Inverse-dT)


top 4-Thio-2'-deoxythymidine (4-Thio-dT)

  • Useful in cross-linking and affinity-labeling experiments

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product scale amount cat. no. price/coupling
4-Thio-dT 0.05 µmol 5 nmol 5-0233-012 99.00 EUR
0.20 µmol 25 nmol 5-0233-013 135.00 EUR
1.00 µmol 100 nmol 5-0233-014 195.00 EUR

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Structure & Reference


top 5-C3-Carboxy-2'-deoxythymidine (5-C3-Carboxy-dT)

  • Useful for introduction of molecules with a primary amine such as antibodies and enzymes by standard coupling procedures

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product scale amount cat. no. price/coupling
5-C3-Carboxy-dT 0.05 µmol 5 nmol 5-0233-112 64.00 EUR
0.20 µmol 25 nmol 5-0233-113 79.00 EUR
1.00 µmol 100 nmol 5-0233-114 115.00 EUR

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Structure & Reference


top 5-C6-Amino-2'-deoxythymidine (5-C6-Amino-dT)

  • Incorporation of internal reporter groups
  • Does not interfere with nucleic acid hybridization
  • Unique ability to provide functional amino groups at internal sites

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product scale amount cat. no. price/coupling
5-C6-Amino-dT 0.05 µmol 5 nmol 5-0233-212 48.50 EUR
0.20 µmol 25 nmol 5-0233-213 64.00 EUR
1.00 µmol 100 nmol 5-0233-214 95.00 EUR

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Structure


top Inverse-2'-deoxythymidine (Inverse-dT)

  • For blocking oligonucleotides from extension or ligation
  • Stabilization against 3'-exonucleases

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product scale amount cat. no. price/coupling
Inverse-dT 0.05 µmol 5 nmol 5-0233-312 64.00 EUR
0.20 µmol 25 nmol 5-0233-313 79.00 EUR
1.00 µmol 100 nmol 5-0233-314 130.00 EUR

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Structure


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